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KMID : 0352719920160030190
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Journal of Ginseng Research
1992 Volume.16 No. 3 p.190 ~ p.197
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Study on the Hypoglycemic Action of Ginseng Saponin on Streptozotocin Induced Diabetic Rats (I)
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Abstract
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The increased level of glucose. Ketone bodies. non-esterified acids and lactate in blood, decrease of glycogen content, phosphofructokinase activity and glucokinase activity and the increased level of glucose-6-phosphatate activity in the liver
of
streptozotocin injected rats were significantly moderated by ginseng saponin administration. It is not likely. However, that the hypoglycemic action of ginseng saponin might be due to their direct action on enzyme activities, since the saponin
effect of
several enzymes in vitro not enough to explain such an appreciable activity of the saponin in streptozotocin induced diabetic rats. for which much work have to be done.
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KEYWORD
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